SAE: Potential Drug Target and Biomarker for Diseases (P15618)

Target Name: SUMO activating enzyme complex

NCBI ID: P15618

Other Name(s): SAE | SUMO E1 activator enzyme complex

SAE: Potential Drug Target and Biomarker for Diseases

SUMO Activating Enzyme Complex (SAE) is a protein complex that is involved in the regulation of cellular processes such as cell division, DNA replication, and metabolism. The SAE is composed of a variety of enzymes that work together to ensure the proper execution of these processes. SAE has been identified as a potential drug target and a biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and metabolic disorders.

The SAE is a protein complex that contains multiple enzymes that are involved in the regulation of cellular processes such as cell division, DNA replication, and metabolism. The SAE is composed of a variety of enzymes that work together to ensure the proper execution of these processes. The SAE plays a crucial role in the regulation of the cell cycle, including the G1 phase, S phase, and G2 phase.

During the G1 phase, the SAE ensures that the cell prepares for cell division by producing necessary proteins and replicating DNA. During the S phase, the SAE helps regulate the replication of DNA by ensuring that the correct number of copies of each gene is replicated. During the G2 phase, the SAE helps prepare the cell for cell division by producing more proteins and organelles that will be needed during the cell division process.

The SAE is also involved in the regulation of metabolism, including the metabolism of nutrients and the production of energy. The SAE helps regulate the levels of nutrients in the cell and ensures that they are used properly during cell division. The SAE also helps regulate the production of energy during the cell cycle by ensuring that the cell has enough ATP to power its processes.

SAE has been identified as a potential drug target for a variety of diseases, including cancer, neurodegenerative diseases, and metabolic disorders. For example, SAE has been shown to be involved in the regulation of the growth and development of cancer cells. Researchers have found that high levels of SAE activity are associated with the development of cancer. Additionally, SAE has been shown to be involved in the regulation of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

SAE is also a potential biomarker for a variety of diseases. The SAE is an essential protein that is involved in the regulation of many cellular processes, including cell division, DNA replication, and metabolism. As such, it is possible that SAE levels may be affected by a variety of diseases. For example, SAE levels may be affected by cancer, neurodegenerative diseases, and metabolic disorders.

In conclusion, SUMO Activating Enzyme Complex (SAE) is a protein complex that is involved in the regulation of cellular processes such as cell division, DNA replication, and metabolism. The SAE is composed of a variety of enzymes that work together to ensure the proper execution of these processes. SAE has been identified as a potential drug target and a biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and metabolic disorders. Further research is needed to fully understand the role of SAE in these diseases and to develop effective treatments.

Protein Name: SUMO Activating Enzyme Complex

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